When it comes to treating erectile dysfunction, a condition where a man can’t get or keep an erection sufficient for sex. Also known as impotence, it affects millions of men worldwide, and two drugs dominate the conversation: Cialis and Viagra. Both are phosphodiesterase-5 inhibitors, but they’re not the same drug, and choosing between them isn’t about which is "better"—it’s about which fits your life.
Cialis (tadalafil) lasts up to 36 hours, which is why some call it the "weekend pill." You can take it once a day at a lower dose for ongoing use, or take it 30 minutes to 2 hours before sex and have flexibility for the rest of the day. Viagra (sildenafil) kicks in faster—about 30 to 60 minutes—but its effects fade after 4 to 6 hours. If you’re planning spontaneity, Cialis gives you room to breathe. If you prefer taking something right before intimacy, Viagra might feel more predictable. Neither works without sexual stimulation, and both can cause headaches, flushing, or upset stomach. But Cialis is more likely to cause back pain or muscle aches, while Viagra can blur vision in rare cases.
People often ask if one is stronger. Not really. Both are effective for most men, but your body reacts differently. If you have a high-fat meal, Viagra’s absorption slows down—Cialis isn’t as affected. If you’re on blood pressure meds, your doctor will check for interactions. Neither is safe with nitrates, and alcohol can make side effects worse with either. What matters most isn’t the brand name—it’s your health history, your schedule, and how your body responds. Many men try one, then switch. There’s no shame in that. What works for your neighbor might not work for you, and that’s normal.
Below, you’ll find real comparisons between these two drugs and their alternatives. You’ll see how they stack up against Vardenafil, Avanafil, and even generic versions. We cover timing, cost, side effects, and what doctors actually recommend based on patient reports. Whether you’re new to ED meds or looking for a change, this collection gives you the facts without the hype.
A 2025 guide comparing high‑dose Cialis (tadalafil) with Viagra, Levitra, Stendra, generic options and natural supplements, covering dosage, onset, cost, side‑effects and how to choose the best ED treatment.
